A performance evaluation and screening method of antioxidants based on programmed ramp method of PDSC (pressurized differential scanning calorimetry) was proposed. By using the PDSC programmed ramp method, the peak temperature of oxidation was measured for the oils with different antioxidants at multiple heating rates. OzawaFlynnwall method and the Kissinger method were used to calculate the kinetic parameters of oxidation. Antioxidation ability of several types of aminetype and phenoltype antioxidants was evaluated. The results show that the PDSC programmed ramp method can be used to evaluate the antioxidation ability of antioxidants. The aminetype antioxidants can decrease the energy of activation of oil samples, which are suitable for high temperature antioxidants, and the phenoltype antioxidants can increase the energy of activation of oil samples, which are suitable for low temperature antioxidants.