In order to study the rolling contact fatigue of harmonic wear wheels of highspeed train,the coupling model combing the harmonic wear wheeltrack system dynamics with wheel circumference predicting fatigue model was established.In the model,first and second nonlinear suspension force of the vehicle system,nonlinear wheel/rail contact geometry were taken into account and the effects of the wheel/rail incentives and rail vibration response on wheel/rail contact creep were also considered.With CRH2 highspeed train as the research object,its dynamics model of rail was established by using multibody dynamics software UM.The wheel creep rate and creep force were analyzed on the most common statistical data,the 1st order,3rd order,6th order and 11th orders of harmonic wear and the wave depth of 01 mm and 03 mm.The harmonic abrasion wheel fatigue characteristics were studied by using the wheel creep characteristic parameters in a different order number and wave depth as the input parameters of the fatigue model.Results show that no harmonic wear wheel is in the elastic stability state,the 1st order harmonic wear wheels with wave depth of 01 mm and 03 mm,and the 6th order and 11th order harmonic wear wheels with wave depth of 01 mm are in a state of ratchet effect,the 6th order and 11th order harmonic wear wheels with wave depth of 03 mm are in the plastic stability state.So the loworder and lowwave depth wheel is given priority to fatigue,highorder and bigwave depth wheel is given priority to abrasion.The rolling contact fatigue and wear of the wheels are more sensitive to the change of wave depth than the change of order,the increase of wave depth will cause the rapid increasing of wheel creep force and creep rate,as well as the tangential force.