The twodimensional axisymmetric model of rotary lip seal was established by using finite element analysis software ABAQUS,and the effect of the structural parameters such as contact width,lowangle and highangle,interference and waist depth on the sealing performance of rotary lip seal was analyzed.The results show that the contact pressure distributions of the rotary lip seal meet the sealing requirements within the range of structural parameters studied.The maximum contact pressure of the rotary lip seal is reduced with the increasing of the contact width,the lowangle and the interference,but increased with raising of the waist thickness.Along with the increasing of the highangle,the maximum contact pressure of the rotary lip seal is increased obviously first and then tended to be slow.With the maximum contact pressure of sealing surface as the optimization target,the structural parameters of the lip seal of the rotary shaft were optimized based on the response surface methodology,and the optimal structural parameters combination scheme was obtained.