In order to study the wheel profile wear of high speed train with different wheel and rail profile matching,a vehicle and track coupling dynamics model of highspeed train was built by using multibody dynamics software UM,and the wheel profile wear law was compared and analyzed when the wheel profile of LMA matches with the rail profiles of CHN60 and UIC60,respectively.The results show that when the operating mileage is less than 265 000 km,the wheel profile wear of LMA/CHN60 and LMA/UIC60 has little difference.When the operating mileage is more than 265 000 km,the wear of LMA/UIC60 is increased significantly.Compared with the LMA/CHN60,the wheel profile wear has a greater influence on the distribution of the contact points of LMA/UIC60,and LMA/CHN60 has better wheelrail contact status than LMA/UIC60.When the operating mileage is less than 135 000 km,the maximum value of the wheel wear work of LMA/CHN60 and LMA/UIC60 has little difference,after that the maximum value of the wheel wear work of LMA/UIC60 is gradually greater than that of LMA/CHN60.The maximum wheel wear power of LMA/CHN60 and LMA/UIC60 is decreased gradually during the operation,but the maximum wear power of the LMA/UIC60 is generally larger.