The accelerated ageing test conditions of molybdenum disulfide lubricating grease in valves were established through time-temperature equation, and the accelerated ageing tests with equivalent 25 ℃ for six years and ten years were carried out.The screw tightening torque coefficients of simulation valves for the molybdenum disulfide lubricating greases with different aging conditions were obtained on the self-made test equipment for force transfer efficiency of simulation valves. The results show that the molybdenum disulfide lubricating grease used in new manual valves has excellent ageing resistance properties. The friction performance of molybdenum disulfide lubricating grease after equivalent ageing test for ten years is similar to the molybdenum disulfide lubricating grease without ageing. The molybdenum disulfide lubricating grease in valves can satisfy the application demand of ten years.