By using ABAQUS finite element analysis software,the twodimensional sliding contact model was established for the flank surface of carbide cutting tool with the titanium alloy in the process of cutting.The stress changes were studied in the process of sliding contacts from the micro perspective.The shape of the asperity on the surface of workpiece and tool was simplified as a semicircle,and the stress distribution was studied between the sliding contact surface of a couple of asperities in different sliding velocity and vertical interference.The results show that at fixed sliding velocity,along with increasing of vertical interference in a certain range,the stress distribution of contact surface of asperity is gradually spreaded inside the asperity,and the stress value is also increased.By the comprehensive experiment design method to do test,the simulation calculation and regression analysis by using MATLAB were carried out.The results show that in a relative short sliding distance,within the range of study,the influence of sliding velocity on stress value can be neglected. 