Linkam FTIR600 temperature control table and Laser DXR Raman microscope were used to make real time monitoring of the Raman signal of trimethylolpropane trioleate (TMPTO) base oil during the oxidation process by continuous temperature rising oxidation and isothermal oxidation experiments on TMPTO.The influence of oxidation temperature and oxidation time on TMPTO base oil and the change of TMPTO base oil chemical constitution were researched.The results show that as the temperature increases,the Raman intensity of the =C—H and C=C stretching vibration and —CH2— deformational vibration weakens gradually.With the increasing of the oxidation time,the Raman intensity of the=C—H and C=C stretching vibration weakens gradually and the Raman intensity of —CH2— deformational vibration remains unchanged,the peak of the C〖FY=,*2〗C stretching vibration is redshifted.When the temperature cools to room temperature,the Raman intensity of =C—H and C=C stretching vibration can recover partially,and the Raman intensity of —CH2— deformational vibration recovers completely.Combined Laser DXR Raman microscope with Linkam FTIR600 temperature control table to research the continuous temperature rising oxidation process is a new effective method to characterize the lubricant structure changes.