A homogeneous experimental design was used to study influence of vulcanization process of 5 independent variables as sulfur and vulcanization accelerant TMTD dosage,vulcanization temperature,time and pressure on compression and rebound performance of nonasbestos gaskets.By using of multiple linear regression method,the relationship between the compression rate and rebound with all process parameters was studied，and a regression model was set up.The results show that the vulcanization temperature,pressure and time have a great influence of on the compression rate.The increase of vulcanization temperature,pressure and time is favorable to decrease the compression rate,while the increase of sulfur content has a negative effect on the compression ratio.Accelerant TMTD dosage and temperature have an interactive influence on the compression rate,and the increasing of TMTD can reduce vulcanization temperature,while the increasing of vulcanization temperature can reduce the TMTD dosage.The performance of the gasket samples prepared under different vulcanization process was predicted by the regression model,and the predicted values were quite close to the practical measured values.