The fretting fatigue properties of high strength cast Aluminum alloy were simulated by ANSYS, and the stress and strain distribution on the contact surface was got.The crack initiation location was predicted based on the SWT critical surface method,the fretting fatigue life prediction parameters were fitted by the experimental values, and the fretting fatigue life was predicted by the critical surface method.The results show that, with the increasing of the axial force, the fretting fatigue life is decreased under the constant clamping force.There is a critical value of axial force, once beyond this critical value, the life of the high strength cast Aluminum alloy component will decrease sharply.The fretting crack initiation location and lifetime of high strength cast Aluminum alloy were experimentally verified on the HYS100 fretting fatigue testing machine.The results show that the predicted results are in agreement with the experimental results, the predicted life and the actual life span are within the limits of the error.