The interfaces with different affinity were generated with different materials of slider surfaces and different lubricants.Under different loads,the relation of film thickness versus speed was measured for different interfaces.The interface affinity was differentiated by the adhesive work,and the correlation of interface affinity and hydrodynamic lubrication was studied.The results show that the contact angle and contact angle hysteresis aren’t the only parameter to judge the relationship between interface affinity and film thickness.High adhesion work is more likely to produce high film thickness for the similar viscosity of lubricants.Loads can influence the interface effect and heavy loads can enhance the interface effect.