The anhydrous ethanol solution of silane coupling agent KH550 and sodium dodecyl benzene sulfonate(SDBS) aqueous solution were used for surface activation treatment of graphene,and the polytetrafluoroethylene(PTFE) compound sealing materials modified by graphene were prepared by coldmould pressing process.The effects of the graphene content and its surface activation treatment method on the properties of composite materials were studied.The results show that surface modification of hydrogen peroxide and SDBS can effectively improve the agglomeration of graphene,and the improvement effect is better than that of KH550.Graphene with content of about 1% can effectively improve the mechanical strength,hardness,compressibility and recovery,creep relaxation properties and sealing performance of the PTFE.The PTFE compound materials modified by graphene have good practical application value.