In order to improve the wear resistance of titanium alloy TC4 artificial hip joint prosthesis,a circular dimple with different parameters was constructed on the surface of titanium alloy sample by laser.The influence of micro-texture parameters on contact angle and friction coefficient was studied by single factor test using contact angle measuring instrument and friction and wear testing machine.The quadratic regression model between pit diameter,pit depth,area ratio and contact angle,friction coefficient was established by response surface method,and the optimal micro-texture parameters were obtained.The results show that the surface contact angle of the titanium alloy is decreased with the increase of the pit diameter,the decrease of the pit depth and area ratio within a given texture range.The friction coefficient of the titanium alloy can be effectively reduced when selecting a small pit depth,a suitable pit area ratio and pit diameter,and the interaction between the pit diameter and the pit area rate has the most significant effect on the friction coefficient.The optimal parameters of the texture are 230 μm in diameter,10 μm in depth and 14% in area ratio.The test results are consistent with the predicted values of the quadratic regression model,which shows that the established quadratic regression model has high reliability.