Chemical synthetic and ball milling nano particles are different in chemical composition,particle size distribution and particle size.In order to study the influence of nano particles prepared by two methods on the anti-wear and friction reduction performance,the tribological performances of serpentine and Kaolin nano particles prepared by different methods were evaluated based on block-ring friction test rig.Experimental results show that the synthetic serpentine particles with diameter of 200 to 800 nm exhibits the lowest friction coefficient and wear,while the ball milling Kaolin shows the highest friction and wear.Synergistic lubricating effect is shown when mixing the synthetic nano serpentine particles and molybdenum friction reduction additive,so the friction coefficient is reduced by 52% compared with pure synthetic serpentine particles,the wear is reduced by 13% compared with MoDTC under the test temperature of 110 ℃ to 130 ℃.At 150 ℃,the synthetic serpentine,ball milling serpentine,and synthetic Kaolin improve the production of MoS2 on friction surface when mixed with MoDTC,which further reduces the friction coefficient.The synthetic serpentine particles show round surface without any sharp edge,which show minimal plough-cutting effect to friction surface.The synthetic serpentine has better anti-wear and friction reduction effect compared with ball milling serpentine.