The fatigue life of brush seal wire was analyzed based on Miner’s linear cumulative damage theory,the S-N curve of brush wire materials was corrected by using the average stress Goodman correction theory,and the fatigue life analysis model of brush seal wire was established by using finite element statics analysis and fatigue life analysis methods.On the basis of verifying the accuracy of numerical model,the structural parameters of brush seal wire fatigue life analysis model were optimized by analyzing the influence of different structural parameters of brush seal wire on the fatigue life of brush wire.The results show that the main failure area of brush seal wire is the root area of brush wire,followed by the middle area of brush wire.Under different structure parameters of the diameter,installation angle and length of brush wire,the fatigue life of the brush wire decreases with the increase of the maximum stress amplitude within the yield stress of the brush wire material.When the brush wire diameter of brush seal is 0.08 mm to 0.12 mm,the inclination angle of brush wire is 45° to 55°,and the length of brush wire is 8 mm to 12 mm,the optimal structural parameters of brush wire fatigue life analysis model of brush seal are obtained.The research can provide theoretical guidance for the design of brush seal.