Polyethylene particles produced by wear can cause a series of problems,such as inflammation,osteolysis,aseptic loosening,etc.,and eventually lead to the failure of artificial joint prosthesis implantation.The current hip joint simulation test standards and common hip joint simulators were introduced,the relevant literatures on the wear performance of CoCrMo/UHMWPE artificial hip prosthesis through hip joint simulation test were reviewed,and the influence on the wear performance of hip joint prosthesis was discussed from six aspects,including ball head diameter,acetabular abduction angle,ball surface roughness,load,protein concentration and material modification.There are consistent views on the influence of ball head diameter,ball head surface roughness and load on the wear performance of hip joint prosthesis,that is,the three parameters are inversely proportional to the wear performance of hip joint prosthesis.While there are still divergent views on the influence of acetabular abduction angle and protein concentration on the wear performance of hip joint prosthesis,which needs to be further explored.The research direction of the prosthesis design and the optimization direction of the test parameters were prospected,which provides some reference and guidance for the optimization design and clinical research of the new generation of hip prosthesis.