The construction of the Sichuan-Tibet Railway is faced two major challenges:extreme geological disasters and 〖JP2〗an extremely poor engineering environment.The spatial complexity of running lines of trains will inevitably affect the wheel-〖JP〗rail wear performance.To investigate the wear law of trains under a complex spatial line environment,the superimposed line conditions of the long slope and the plane curve was set up according to the line design parameters of the Sichuan-Tibet Railway.The high-speed train dynamics model and the wheel wear prediction model were established,and the wheel wear characteristics of the high-speed train running on long slopes under the condition of traction and braking were analyzed.The results shows that when CR400-AF high-speed train with LMA wheel tread runs on the slope-curve superimposed road conditions,the wheel-rail contact state of the front bogie is two-point contact,and the wheel-rail contact state of the rear bogie is single-point contact.The relative position of the plane curve and the ramp has a certain influence on the wheel wear of the train.As the radius of the curve increases,the wheel wear depth decreases gradually,and the decreasing trend is getting smaller.There are critical mileage and critical speed during the long-term operation of the train on the slope-curve road condition.In order to prevent the severe wear of the wheel,it is recommended to avoid running at the critical speed or lower speed as much as possible during the long-term operation of the high-speed train,and the wheels should be repaired in time when the operating mileage exceeds the critical mileage.