In order to explore the mixed lubrication performance of water lubricated rubber stern bearing with axis misalignment along the end face under large eccentricity(ε≥1) ,a method for calculating the film thickness of journal bearing with arbitrary axis misalignment along the end face under large eccentricity was presented,and was applied to the analysis of mixed lubrication performance of scale model of water lubricated rubber stern bearings.The variety rule of water film pressure and contact pressure distribution with misalignment angle under heavy load conditions was obtained by numerical simulation,and the effect of misalignment angle,misalignment directional angle on mixed lubrication performance of water lubrication rubber stern bearing was investigated.The results shown that under mixed lubrication stage,the axis misalignment along the end face has slightly effect on fluid pressure,but it will significantly enhance the contact effect of lubrication interface and deteriorate its lubrication performance.Increasing the misalignment directional angle will improve the load capacity of water lubricated rubber stern bearing in a certain degree.The maximum water film pressure will move reversely along the deflection end face when the misalignment angle increases to a certain extent.The influence of deflection angle on the lubrication performance of water lubricated bearings is more significant in the mixed lubrication stage,and the influence will be weakened in the elastohydrodynamic lubrication stage.